Febrile man in hospital. He was coughing up phlegm yellow >>. << He also complained of chest pain. Breath sound
appear crackling. proposed a dense left lower lobe
consolidation. Hematologic studies showed leukocytosis. What is your diagnosis? This is a case of acute lower respiratory infection, possibly
partial pneumonia. What are bacterial pathogens of pneumonia? Pneumonia can be caused by bacteria such as Streptococcus
pneumonia (pneumococcus), Hemophilus influenza, Klebsiella
pneumonia, Staphylococcus aureus. Other less pathogenic bacteria
include Legionella Pneumophila and Pseudomonas aeruginosa. People
with poor oral hygiene, changes in swallowing reflexes or impaired consciousness
prone to infection due to anaerobes
desire oral fluid. Mycoplasma pneumonia is known to cause
primary atypical pneumonia. The fact that the samples collected? The patient was asked to spit into a sterile container. In Hospice samples such as bronchial washing specimen
transtrahealnoy or aspiration can be taken. Blood can be collected
blood culture. As the sample is processed? Gram stained smear should be made out of thick mucus >> << and there is pus cells and bacteria. A good example
should be less than 10 epithelial cells and more than 25
pus cells per low power field. Sputum
<< to be vaccinated >> or, preferably in. What are your observations? showed many pus cells with gram positive
lanceolate form cocci in pairs. Small, round, smooth colonies with >> << have been seen on blood agar. How do you define growth? showed gram-positive >> << lanceolate form cocci in pairs indicate the pneumococcus. These colonies were
bile solubility, inulin
fermentation, optochin susceptibility, the reaction capsule swelling reaction and mouse
. intraperitoneal inoculation may be made to differentiate
pneumococci with viridens streptococci. Pneumococcus positive >> << to, inulin fermentation reaction capsule swelling reaction is
and are pathogenic for mice. Capsule antgien
be found >> << or co-agglutination. What is the reaction capsule swelling reaction? Neufeld in also known as capsule
swelling reaction. When the suspension of pneumococcal colonies
treated with loop serum containing anitbodies in capsular polysaccharide >> << and observed under a microscope, appears capsule
swollen. The binding of antibodies to the capsular antigen is
to change the refractive index, making it swollen. Drops of methylene blue may be added to the suspension
provide contrast. Serum can be used monovalent or polyvalent (omniserum). What optochin susceptibility? Optochin is ethyl hydrocuprein hydrochloride, disc 5 mg strength >> << is located on the lawn culture of pneumococcus and
incubate. Great >> << (at least 10-13 mm in diameter) around the disk indicates
sensitivity. What is the bile solubility test? Pneumococcus have amidaznoy enzymes due to autolysis. These enzymes
can be activated surface-active substances such as salts of bile acids.
Bile solubility test can be done in
inch or for turbid, 1 ml of culture broth night
pneumococci,
add a few drops of 10% sodium dezoksyholat leads to clearance of the broth
15 minutes. Colonies probably pneumococci isolated and loopful
2% sodium dezoksyholat placed upon them, and incubated in
37
C for 30 minutes.
The disappearance of colonies leaving the field of alpha-hemolysis
indicates a positive test. What is the pathogenesis of pneumococcal pneumonia? Pneumonia is defined as inflammation and consolidation >> << lung tissue due to an infectious agent. Pneumococcus range
light after the first colonization of the oropharynx. S pneumonia
generally located in the nasopharynx and is
asymptomatically in approximately 50% of healthy people. Viral infections, pneumococcal increase investment in >> << receptors on activated airway epithelium. The presence of capsule
main factor of virulence, as it helps the bacteria avoid phagocytosis
. Pneumonic plague progresses as pneumococcus
multiply in alveoli and alveolar epithelium to invade. Pneumococcus has spread from the alveoli into the alveoli, thereby making
inflammation and consolidation of partial sections. Dappled >> << bronchopneumonic picture with lower fractions observed in >> << elderly. In S. pneumonia infection tends to attract
pleura, pleurisy often seen. What other infections of pneumococcus? Pneumococci are known to cause sinusitis, otitis media, septic arthritis
, sepsis, meningitis and endocarditis. What are antibiotics used to treat strattera price this condition <<? Penicillin >> still the drug of choice, but many strains
currently developing resistance through changes in the
penicillin binding proteins. Alternative selections include
macrolides (erythromycin, roksytromitsyn, clindamycin), quinolones
(ciprofloxacin, levofloxacin), cephalosporins (cefuroxime,
tsefpodoksym, cefotaxime). Many penicillin-resistant strains
also resistant to erythromycin, kotrimoksazol, tetracycline, chloramphenicol and
. Choosing the appropriate antibiotic should be made
after all. What conditions may predispose to pneumococcal infections? Chronic alcoholism, splenectomy, pre-SARS
diseases, malnutrition, chronic smoking, cirrhosis,
ischemic heart disease, etc. Is there a vaccine against pneumococcal infection? 23-valent vaccine polysaharydnoy 23 most common serotypes was
used in some countries. 23-valent pneumococcal polysaccharide vaccine
was recommended for use in
children from 2 years old who have high levels of diseases, including >> << those with sickle cell disease (VSS), chronic diseases of primary
human immunodeficiency virus (HIV), or others who
immunocompromised. 23-valent pneumococcal polysaccharide vaccine
effective in preventing invasive pneumococcal infections in
older children and adults, these vaccines do not protect children
at the age of 2 years. 7-valent pneumococcal protein polysaharydnoy
combined vaccine was licensed for use among children and young people
children, as it reduces and prevents pneumococcal colonization >> << diseases among children under 2 years. .
No comments:
Post a Comment